Analgin, 500 mg tablets
Analgin (metamizole) is a medicine of the pyrazolone group, possessing hard analgesic and antipyretic effects and moderate antiinflammatory activity. Blocking of the synthesis of endogenous pyrogens – prostaglandins D and E – is the cause for the antipyretic activity and also for the analgesic action of this drug. The decrease of the prostaglandis production in the periphery (and respective decrease of nerve endings sensitivity) plays a relatively smaller role. In contrast to the other nonnarcotic analgesic drugs, metamizole stimulates the release of β-endorphins, explaining its activity in cases of visceral pain. Metamizole has a slight spasmolytic activity on the smooth muscle cells of the biliary and urinary tracts and also on the muscle of the uterus.
| Pharmacie | |
| Conseils | Analgin tablets are used for the treatment of pains of different origin and variable intensity: -toothache, headache, arthralgia, neuralgia, myalgia (in case of other analgesic medications inefficiency); -fever with colds and infectious-inflammatory diseases.The dosage and duration of the treatment must be determined according to the severity of the pain syndrome. The common dose in the adults is 250 to 500 mg (1/2 to 1 tablet) ), every 8-12 hour. The maximum single dose – 1 g, and 3 g/daily. In over 15 year-old children the Analgin dose is 250 mg (1/2-1 tab), every 8-12 hours. |
| Description | Do not exceed the recommended dose prescribed by your doctor. Caution should be used on patients with malabsorption of glucose or galactose, galactosemia or deficiency of lactase, as the product contains 11.8 mg of lactose in 1 tablet. Not recommended for regular long-term use due to myelotoxicity. Exclude the use to treat acute pain in the abdomen (to determine the cause). The appointment of patients with acute cardiovascular disease should be closely monitored for hemodynamics. Used with caution in patients with blood pressure below 100 mm Hg, with a history of indications for kidney disease (pyelonephritis, glomerulonephritis) and with long-term alcohol anamnesis. There is possible red coloration of urine due to excretion of metabolites during applying Analgin. Effects on ability to drive vehicles and management mechanisms With high doses of Analgin avoid activities that require high concentration and rapid psychomotor reactions. |








































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